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Dr. Sriranganathan's research focuses on investigating the protective antigens of Brucella and their role in immunity. Utilizing current recombinant DNA technology and conventional mutagenesis, he is developing more effective DNA vaccine candidates against Brucellosis. Brucellosis vaccine development is the most active area of his team effort. The focus group, located at the Center for Molecular Medicine and Infectious Diseases, has attracted not only USDA funding, but also have established a working relationship with the U.S. Army in a joint Cooperative Research and Exchange Development Agreement (CREDA). The major source of present funding for VetTech's Brucellosis research effort comes from the National Institutes of Health and the USDA.
Dr. Sriranganathan is also active in the area of phage based remediation of foodborne Salmonella in poultry and has been successful in attracting poultry industry funding. Using these and internal funding, the entire 86.155kb chromosomal sequence of one broad Salmonella species-specific phage called Felix 01 has been determined. It has been deposited at the GenBank and will be published. With support from bioremediation Industry, he has also been exploring bioremediation processes to treat regulated medical waste.
For the past 18 years, Dr. Sriranganathan has been the course leader of veterinary bacteriology and mycology class taught for sophomore veterinary students. He is actively involved in the curriculum development and has developed several web-based teaching tools.
Dr. Sriranganathan is active in committees, panels and commissions at the veterinary medical school. This includes participation on the school's Admissions and Standards Committee, Research and Graduate Studies Board and University Radiation Safety Committee. Presently he serves on the College's Curriculum Board and the Accreditation Committee. He is also a long time member of the American Society for Microbiology, the American Association of Veterinary Laboratory Diagnosticians, and the American College of Veterinary Microbiologists.